Tristetraprolin Mediates Radiation-Induced TNF-α Production in Lung Macrophages

The efficacy of radiation therapy for lung cancer is limited by radiation-induced lung toxicity (RILT). Although tumor necrosis factor-alpha (TNF-α) signaling plays a critical role in RILT, the molecular regulators of radiation-induced TNF-α production remain unknown. We investigated the role of a m...

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Main Authors: Ray, Dipankar, Shukla, Shirish, Allam, Uday Sankar, Helman, Abigail, Ramanand, Susmita Gurjar, Tran, Linda, Bassetti, Michael, Krishnamurthy, Pranathi Meda, Rumschlag, Matthew, Paulsen, Michelle, Sun, Lei, Shanley, Thomas P., Ljungman, Mats, Nyati, Mukesh K., Zhang, Ming, Lawrence, Theodore S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585360/
https://ncbi.nlm.nih.gov/pubmed/23468959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057290
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