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Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication

Like tumor cells, DNA viruses have had to evolve mechanisms that uncouple cellular replication from the many intra- and extracellular factors that normally control it. Here we show that adenovirus encodes two proteins that activate the mammalian target of rapamycin (mTOR) for viral replication, even...

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Autors principals: O'Shea, Clodagh, Klupsch, Kristina, Choi, Serah, Bagus, Bridget, Soria, Conrado, Shen, Jerry, McCormick, Frank, Stokoe, David
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC556401/
https://ncbi.nlm.nih.gov/pubmed/15775987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600597
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