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THE ROLE OF THE mTOR NUTRIENT SIGNALING PATHWAY IN CHONDROCYTE DIFFERENTIATION
The mammalian Target of Rapamycin (mTOR) is a nutrient-sensing protein kinase that regulates numerous cellular processes. Physilogical fetal rat metatarsal explant cultures were used, to study the effect of mTOR inhibition on chondrogenesis. Insulin significantly enhanced bone growth. Rapamycin sign...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768549/ https://ncbi.nlm.nih.gov/pubmed/18265001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21464 |
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