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Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development
Germline mutations of the SMARCB1 gene predispose to two distinct tumor syndromes: rhabdoid tumor predisposition syndrome, with malignant pediatric tumors mostly developing in brain and kidney, and familial schwannomatosis, with adulthood benign tumors involving cranial and peripheral nerves. The me...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563506/ https://ncbi.nlm.nih.gov/pubmed/28824165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00346-5 |
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