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Familial occurrence of schwannomas and malignant rhabdoid tumour associated with a duplication in SMARCB1

BACKGROUND: The role of germline and somatic SMARCB1 gene mutations in malignant rhabdoid tumour (MRT) predisposition is well known. Germline SMARCB1 mutations have also recently been identified in a subset of individuals with schwannomatosis. Surprisingly, MRT predisposition and schwannomatosis hav...

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Detalhes bibliográficos
Main Authors: Swensen, J J, Keyser, J, Coffin, C M, Biegel, J A, Viskochil, D H, Williams, M S
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843150/
https://ncbi.nlm.nih.gov/pubmed/19124645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2008.060152
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