The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation

Rhabdoid tumours (RTs) are highly aggressive tumours of infancy, frequently localized in the central nervous system (CNS) where they are termed atypical teratoid/rhabdoid tumours (AT/RTs) and characterized by bi-allelic inactivation of the SMARCB1 tumour suppressor gene. In this study, by temporal c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Han, Zhi-Yan, Richer, Wilfrid, Fréneaux, Paul, Chauvin, Céline, Lucchesi, Carlo, Guillemot, Delphine, Grison, Camille, Lequin, Delphine, Pierron, Gaelle, Masliah-Planchon, Julien, Nicolas, André, Ranchère-Vince, Dominique, Varlet, Pascale, Puget, Stéphanie, Janoueix-Lerosey, Isabelle, Ayrault, Olivier, Surdez, Didier, Delattre, Olivier, Bourdeaut, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738337/
https://ncbi.nlm.nih.gov/pubmed/26818002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10421
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