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TMOD-15. SPATIOTEMPORAL LOSS OF SMARCB1 IN EARLY NEURAL CREST LINEAGE LEADS TO DIFFERENT MOLECULAR SUBTYPES OF RHABDOID TUMORS
Rhabdoid tumor predisposition syndrome 1 (RTPS1) results from inactivation of the tumor-suppressor SMARCB1, a core component of the BAF (hSWI/SNF) complex. Rhabdoid tumors (RTs) are a highly malignant group of neoplasms that usually occur in children less than 2 years of age, which have no effective...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477260/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.252 |
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