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Profound changes in miRNA expression during cancer initiation by aflatoxin B(1) and their abrogation by the chemopreventive triterpenoid CDDO-Im

Aflatoxin B(1) (AFB(1)) is a potent human and animal hepatocarcinogen. To investigate the effects of aflatoxin on miRNA expression during the initiation phase of carcinogenesis, next-generation sequencing was used to analyze liver tissues from F344 rats exposed to 200 μg/kg per day AFB(1) for 4 week...

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Bibliografiska uppgifter
I publikationen:Mol Carcinog
Huvudupphovsmän: Livingstone, Merricka C., Johnson, Natalie M., Roebuck, Bill D., Kensler, Thomas W., Groopman, John D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563488/
https://ncbi.nlm.nih.gov/pubmed/28218475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22635
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