Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
Several mutations in PTEN-induced putative kinase 1 (PINK1) gene have been reported to be associated with recessive parkinsonism. The encoded protein is predicted to be a Ser/Thr protein kinase targeted to mitochondria. In this study, we have investigated the effects of mutations on PINK1 kinase act...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15824318/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0500617102 |
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