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Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis

For faithful chromosome segregation, the formation of stable kinetochore–microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined. Here, we show that polo-like kinase 1 (Plk1), which is instrumental in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ikeda, Masanori, Tanaka, Kozo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562746/
https://ncbi.nlm.nih.gov/pubmed/28821799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09114-3
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