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Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis
For faithful chromosome segregation, the formation of stable kinetochore–microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined. Here, we show that polo-like kinase 1 (Plk1), which is instrumental in...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5562746/ https://ncbi.nlm.nih.gov/pubmed/28821799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09114-3 |
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