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Cathepsin K knockout protects against cardiac dysfunction in diabetic mice

Diabetes is a major risk factor for cardiovascular disease and the lysosomal cysteine protease cathepsin K plays a critical role in cardiac pathophysiology. To expand upon our previous findings, we tested the hypothesis that, knockout of cathepsin K protects against diabetes-associated cardiac anoma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guo, Rui, Hua, Yinan, Rogers, Olivia, Brown, Travis E., Ren, Jun, Nair, Sreejayan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562704/
https://ncbi.nlm.nih.gov/pubmed/28821796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09037-z
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