Cathepsin K Knockout Alleviates Pressure Overload–Induced Cardiac Hypertrophy

Evidence from human and animal studies has documented elevated levels of lysosomal cysteine protease cathepsin K in failing hearts. Here, we hypothesized that ablation of cathepsin K mitigates pressure overload–induced cardiac hypertrophy. Cathepsin K knockout mice and their wild-type littermates we...

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Bibliographic Details
Main Authors:	Hua, Yinan, Xu, Xihui, Shi, Guo-Ping, Chicco, Adam J., Ren, Jun, Nair, Sreejayan
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3929275/ https://ncbi.nlm.nih.gov/pubmed/23529168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00947
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Cathepsin K Knockout Alleviates Pressure Overload–Induced Cardiac Hypertrophy

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