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Cathepsin K knockout alleviates aging-induced cardiac dysfunction
Aging is a major risk factor for cardiovascular disease. It has previously been shown that protein levels of cathepsin K, a lysosomal cysteine protease, are elevated in the failing heart and that genetic ablation of cathepsin K protects against pressure overload-induced cardiac hypertrophy and contr...
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| Publicado no: | Aging Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406663/ https://ncbi.nlm.nih.gov/pubmed/25692548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12276 |
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