Estrogens and androgens inhibit association of RANKL with the pre-osteoblast membrane through post-translational mechanisms

We have recently demonstrated that RUNX2 promoted, and 17β-Estradiol (E2) diminished, association of RANKL with the cell membrane in pre-osteoblast cultures. Here we show that, similar to E2, dihydrotestosterone (DHT) diminishes association of RANKL, and transiently transfected GFP-RANKL with the pr...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Martin, Anthony, Yu, Jiali, Xiong, Jian, Khalid, Aysha B., Katzenellenbogen, Benita, Kim, Sung Hoon, Katzenellenbogen, John A., Malaivijitnond, Suchinda, Gabet, Yankel, Krum, Susan A., Frenkel, Baruch
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562539/
https://ncbi.nlm.nih.gov/pubmed/28213978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25862
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