Llwytho...

Evaluation of analgesia, tolerance and the mechanism of action of morphine-6-O-sulfate across multiple pain modalities in Sprague-Dawley rats

BACKGROUND: Morphine-6-O-sulfate (M6S) is a mixed μ-/δ-opioid receptor (OR) agonist and potential alternative to morphine for treatment of chronic multimodal pain. METHOD: To provide more support for this hypothesis, the antinociceptive effects of M6S and morphine were compared in tests that access...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anesth Analg
Prif Awduron: Yadlapalli, Jai Shankar K., Dogra, Navdeep, Walbaum, Anqi W., Wessinger, William D., Prather, Paul L., Crooks, Peter A., Dobretsov, Maxim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561516/
https://ncbi.nlm.nih.gov/pubmed/28489639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000002006
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