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Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague–Dawley rats
BACKGROUND: In addition to its classical effects on opioid receptors, morphine can activate glia and stimulate the production of pro-inflammatory immune molecules which in turn counteract the analgesic properties of morphine. We hypothesized that decreased morphine analgesia in females may be the re...
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| Publicado no: | Biol Sex Differ |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4676821/ https://ncbi.nlm.nih.gov/pubmed/26693004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-015-0049-3 |
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