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Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors

This study determined the antinociceptive effects of morphine and morphine-6-O-sulphate (M6S) in both normal and diabetic rats, and evaluated the comparative role of mu-opioid receptors (mu-ORs) and delta-opioid receptors (delta-ORs) in the antinociceptive action of these opioids. In vitro character...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Yadlapalli, Jai Shankar K., Ford, Benjamin M., Ketkar, Amit, Wan, Anqi, Penthala, Narasimha R., Eoff, Robert L., Prather, Paul L., Dobretsov, Maxim, Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107169/
https://ncbi.nlm.nih.gov/pubmed/27637375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.09.012
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