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Role of kappa and delta opioid receptors in mediating morphine-induced antinociception in morphine tolerant infant rats

We have previously noted that the antinociceptive efficacy of morphine was significantly decreased in rat pups chronically infused with morphine from implanted osmotic minipumps. In this study, morphine was fully efficacious (i.e., 100% maximum possible effect, %MPE) in the 52 ºC tail-immersion test...

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Detalhes bibliográficos
Main Authors: Stoller, Dawn C., Sim-Selley, Laura J., Smith, Forrest L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159155/
https://ncbi.nlm.nih.gov/pubmed/17300766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.01.028
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