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Region-dependent attenuation of μ opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance
BACKGROUND AND PURPOSE: Chronic morphine administration produces tolerance in vivo and attenuation of μ opioid receptor (MOR)-mediated G-protein activation measured in vitro, but the relationship between these adaptations is not clear. The present study examined MOR-mediated G-protein activation in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189837/ https://ncbi.nlm.nih.gov/pubmed/17572699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707328 |
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