Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins

High titer autoantibodies produced by B lymphocytes are clinically important features of many common autoimmune diseases. APECED patients with deficient autoimmune regulator (AIRE) gene collectively display a broad repertoire of high titer autoantibodies, including some which are pathognomonic for m...

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Udgivet i:Front Immunol
Main Authors: Fishman, Dmytro, Kisand, Kai, Hertel, Christina, Rothe, Mike, Remm, Anu, Pihlap, Maire, Adler, Priit, Vilo, Jaak, Peet, Aleksandr, Meloni, Antonella, Podkrajsek, Katarina Trebusak, Battelino, Tadej, Bruserud, Øyvind, Wolff, Anette S. B., Husebye, Eystein S., Kluger, Nicolas, Krohn, Kai, Ranki, Annamari, Peterson, Hedi, Hayday, Adrian, Peterson, Pärt
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561390/
https://ncbi.nlm.nih.gov/pubmed/28861084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00976
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