IL-22 Paucity in APECED Is Associated With Mucosal and Microbial Alterations in Oral Cavity

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is caused by recessive mutations in the AIRE gene. The hallmark of the disease is the production of highly neutralizing autoantibodies against type I interferons and IL-22. Considering the importance of IL-22 in maintaining muco...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kaleviste, Epp, Rühlemann, Malte, Kärner, Jaanika, Haljasmägi, Liis, Tserel, Liina, Org, Elin, Trebušak Podkrajšek, Katarina, Battelino, Tadej, Bang, Corinna, Franke, Andre, Peterson, Pärt, Kisand, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232598/
https://ncbi.nlm.nih.gov/pubmed/32477345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00838
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