Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

Chronic mucocutaneous candidiasis (CMC) is frequently associated with T cell immunodeficiencies. Specifically, the proinflammatory IL-17A–producing Th17 subset is implicated in protection against fungi at epithelial surfaces. In autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED,...

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Auteurs principaux: Kisand, Kai, Bøe Wolff, Anette S., Podkrajšek, Katarina Trebušak, Tserel, Liina, Link, Maire, Kisand, Kalle V., Ersvaer, Elisabeth, Perheentupa, Jaakko, Erichsen, Martina Moter, Bratanic, Nina, Meloni, Antonella, Cetani, Filomena, Perniola, Roberto, Ergun-Longmire, Berrin, Maclaren, Noel, Krohn, Kai J. E., Pura, Mikuláš, Schalke, Berthold, Ströbel, Philipp, Leite, Maria Isabel, Battelino, Tadej, Husebye, Eystein S., Peterson, Pärt, Willcox, Nick, Meager, Anthony
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2010
Sujets:
Brief Definitive Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822605/
https://ncbi.nlm.nih.gov/pubmed/20123959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091669
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