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Hydrogen peroxide generated extracellularly by receptor–ligand interaction facilitates cell signaling

Reactive oxygen species (ROS) are key components of postreceptor intracellular signaling pathways; however, the role of ROS in signal initiation is uncertain. We discovered that receptor–ligand interaction caused the generation of hydrogen peroxide (H(2)O(2)). Using members of the hematopoietin rece...

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Detalhes bibliográficos
Main Authors: DeYulia, Garrett J., Cárcamo, Juan M., Bórquez-Ojeda, Oriana, Shelton, Christopher C., Golde, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556007/
https://ncbi.nlm.nih.gov/pubmed/15795385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501154102
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