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Hydrogen peroxide generated extracellularly by receptor–ligand interaction facilitates cell signaling
Reactive oxygen species (ROS) are key components of postreceptor intracellular signaling pathways; however, the role of ROS in signal initiation is uncertain. We discovered that receptor–ligand interaction caused the generation of hydrogen peroxide (H(2)O(2)). Using members of the hematopoietin rece...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC556007/ https://ncbi.nlm.nih.gov/pubmed/15795385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501154102 |
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