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Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element

Until recently, stem cells were thought to be endowed with unlimited self-renewal capacity and, thus, assumed exempt from aging. But accumulating evidence over the past decade compellingly argues that a measurable and progressive replicative impairment in the hematopoietic, intestinal, and muscle st...

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Detalhes bibliográficos
Main Authors: Geiger, Hartmut, Rennebeck, Gabriela, Van Zant, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC555968/
https://ncbi.nlm.nih.gov/pubmed/15788535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408654102
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