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Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells

To test the hypothesis that aging has negative effects on stem-cell homing and engraftment, young or old C57BL/6 bone marrow (BM) cells were injected, using a limiting-dilution, competitive transplantation method, into old or young Ly5 congenic mice. Numbers of hematopoietic stem cells (HSCs) and pr...

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書目詳細資料
Main Authors: Liang, Ying, Van Zant, Gary, Szilvassy, Stephen J.
格式: Artigo
語言:Inglês
出版: The American Society of Hematology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895199/
https://ncbi.nlm.nih.gov/pubmed/15827136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-11-4282
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