Cytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells

Adhesion is a key component of hematopoietic stem cell regulation mediating homing and retention to the niche in the bone marrow. Here, using an RNA interference screen, we identify cytohesin 1 (CYTH1) as a critical mediator of adhesive properties in primary human cord blood–derived hematopoietic st...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Rak, Justyna, Foster, Katie, Potrzebowska, Katarzyna, Talkhoncheh, Mehrnaz Safaee, Miharada, Natsumi, Komorowska, Karolina, Torngren, Therese, Kvist, Anders, Borg, Åke, Svensson, Lena, Bonnet, Dominique, Larsson, Jonas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335807/
https://ncbi.nlm.nih.gov/pubmed/27899358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-720649
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