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Successive stages of amyloid-β self-assembly characterized by solid state nuclear magnetic resonance with dynamic nuclear polarization
Self-assembly of amyloid-β (Aβ) peptides in human brain tissue leads to neurodegeneration in Alzheimer's disease (AD). Amyloid fibrils, whose structures have been extensively characterized by solid state nuclear magnetic resonance (ssNMR) and other methods, are the thermodynamic end point of Aβ...
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| Vydáno v: | J Am Chem Soc |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5559291/ https://ncbi.nlm.nih.gov/pubmed/26068174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04843 |
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