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Effect of ATP and regulatory light-chain phosphorylation on the polymerization of mammalian nonmuscle myosin II

Addition of 1 mM ATP substantially reduces the light scattering of solutions of polymerized unphosphorylated nonmuscle myosin IIs (NM2s), and this is reversed by phosphorylation of the regulatory light chain (RLC). It has been proposed that these changes result from substantial depolymerization of u...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Liu, Xiong, Billington, Neil, Shu, Shi, Yu, Shu-Hua, Piszczek, Grzegorz, Sellers, James R., Korn, Edward D.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559010/
https://ncbi.nlm.nih.gov/pubmed/28739905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702375114
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