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Effect of ATP and regulatory light-chain phosphorylation on the polymerization of mammalian nonmuscle myosin II

Addition of 1 mM ATP substantially reduces the light scattering of solutions of polymerized unphosphorylated nonmuscle myosin IIs (NM2s), and this is reversed by phosphorylation of the regulatory light chain (RLC). It has been proposed that these changes result from substantial depolymerization of u...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liu, Xiong, Billington, Neil, Shu, Shi, Yu, Shu-Hua, Piszczek, Grzegorz, Sellers, James R., Korn, Edward D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559010/
https://ncbi.nlm.nih.gov/pubmed/28739905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702375114
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