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Effect of ATP and regulatory light-chain phosphorylation on the polymerization of mammalian nonmuscle myosin II

Addition of 1 mM ATP substantially reduces the light scattering of solutions of polymerized unphosphorylated nonmuscle myosin IIs (NM2s), and this is reversed by phosphorylation of the regulatory light chain (RLC). It has been proposed that these changes result from substantial depolymerization of u...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Liu, Xiong, Billington, Neil, Shu, Shi, Yu, Shu-Hua, Piszczek, Grzegorz, Sellers, James R., Korn, Edward D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559010/
https://ncbi.nlm.nih.gov/pubmed/28739905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702375114
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