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Effect of ATP and regulatory light-chain phosphorylation on the polymerization of mammalian nonmuscle myosin II

Addition of 1 mM ATP substantially reduces the light scattering of solutions of polymerized unphosphorylated nonmuscle myosin IIs (NM2s), and this is reversed by phosphorylation of the regulatory light chain (RLC). It has been proposed that these changes result from substantial depolymerization of u...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Liu, Xiong, Billington, Neil, Shu, Shi, Yu, Shu-Hua, Piszczek, Grzegorz, Sellers, James R., Korn, Edward D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559010/
https://ncbi.nlm.nih.gov/pubmed/28739905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702375114
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