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Effect of ATP and regulatory light-chain phosphorylation on the polymerization of mammalian nonmuscle myosin II
Addition of 1 mM ATP substantially reduces the light scattering of solutions of polymerized unphosphorylated nonmuscle myosin IIs (NM2s), and this is reversed by phosphorylation of the regulatory light chain (RLC). It has been proposed that these changes result from substantial depolymerization of u...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5559010/ https://ncbi.nlm.nih.gov/pubmed/28739905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702375114 |
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