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Modulating cancer cell survival by targeting intracellular cholesterol transport

BACKGROUND: Demand for cholesterol is high in certain cancers making them potentially sensitive to therapeutic strategies targeting cellular cholesterol homoeostasis. A potential approach involves disruption of intracellular cholesterol transport, which occurs in Niemann–Pick disease as a result of...

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Publicat a:Br J Cancer
Autors principals: Kuzu, Omer F, Gowda, Raghavendra, Noory, Mohammad A, Robertson, Gavin P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558686/
https://ncbi.nlm.nih.gov/pubmed/28697173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.200
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