Identifying the structure-activity relationship of leelamine necessary for inhibiting intracellular cholesterol transport

Leelamine is an anticancer chemotherapeutic agent inhibiting intracellular cholesterol transport. Cell death mediated by leelamine occurs due to the lysosomotropic property of the compound, its accumulation in the lysosome, and inhibition of cholesterol transport leading to lack of availability for...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Gowda, Raghavendra, Inamdar, Gajanan S., Kuzu, Omer, Dinavahi, Saketh S., Krzeminski, Jacek, Battu, Madhu Babu, Voleti, Sreedhara R., Amin, Shantu, Robertson, Gavin P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438648/
https://ncbi.nlm.nih.gov/pubmed/28423677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16002
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