Identification of WEE1 as a target to make AKT inhibition more effective in melanoma

AKT3 is one of the major therapeutic targets in melanoma but clinically targeting AKT3 alone seems to be an ineffective therapeutic approach. To identify unique strategies to enhance the efficacy of targeting AKT3, a screen was undertaken where AKT3 was co-targeted with a panel of kinases important...

詳細記述

保存先:
書誌詳細
出版年:Cancer Biol Ther
主要な著者: Kuzu, Omer F., Gowda, Raghavendra, Sharma, Arati, Noory, Mohammad A., Kardos, Gregory, Madhunapantula, SubbaRao V., Drabick, Joseph J., Robertson, Gavin P.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2017
主題:
Research Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790369/
https://ncbi.nlm.nih.gov/pubmed/28853983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1360446
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