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Identification of WEE1 as a target to make AKT inhibition more effective in melanoma
AKT3 is one of the major therapeutic targets in melanoma but clinically targeting AKT3 alone seems to be an ineffective therapeutic approach. To identify unique strategies to enhance the efficacy of targeting AKT3, a screen was undertaken where AKT3 was co-targeted with a panel of kinases important...
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| Publicado en: | Cancer Biol Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5790369/ https://ncbi.nlm.nih.gov/pubmed/28853983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1360446 |
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