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Conformational Heterogeneity in the Activation Mechanism of Bax
Bax is known for its pro-apoptotic role within the mitochondrial pathway of apoptosis. However, the mechanism for transitioning Bax from cytosolic to membrane-bound oligomer remain elusive. Previous nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) studies defined monomeric...
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| Udgivet i: | Structure |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5558158/ https://ncbi.nlm.nih.gov/pubmed/28712810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.06.009 |
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