Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles

Mutations in many centriolar protein-encoding genes cause primary microcephaly. Using super-resolution and electron microscopy, we find that the human microcephaly protein, RTTN, is recruited to the proximal end of the procentriole at early S phase, and is located at the inner luminal walls of centr...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Chen, Hsin-Yi, Wu, Chien-Ting, Tang, Chieh-Ju C., Lin, Yi-Nan, Wang, Won-Jing, Tang, Tang K.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558016/
https://ncbi.nlm.nih.gov/pubmed/28811500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00305-0
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares