PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN

Centrosome structure, function, and number are finely regulated at the cellular level to ensure normal mammalian development. Here, we characterize PPP1R35 as a novel bona fide centrosomal protein and demonstrate that it is critical for centriole elongation. Using quantitative super-resolution micro...

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Vydáno v:eLife
Hlavní autoři: Sydor, Andrew Michael, Coyaud, Etienne, Rovelli, Cristina, Laurent, Estelle, Liu, Helen, Raught, Brian, Mennella, Vito
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2018
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141234/
https://ncbi.nlm.nih.gov/pubmed/30168418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37846
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