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PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN
Centrosome structure, function, and number are finely regulated at the cellular level to ensure normal mammalian development. Here, we characterize PPP1R35 as a novel bona fide centrosomal protein and demonstrate that it is critical for centriole elongation. Using quantitative super-resolution micro...
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| Gepubliceerd in: | eLife |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
eLife Sciences Publications, Ltd
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6141234/ https://ncbi.nlm.nih.gov/pubmed/30168418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37846 |
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