Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly

Centrioles are cylindrical structures that are usually composed of nine triplets of microtubules (MTs) organized around a cartwheel-shaped structure. Recent studies have proposed a structural model of the SAS-6-based cartwheel, yet we do not know the molecular detail of how the cartwheel participate...

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Main Authors: Lin, Yu-Chih, Chang, Ching-Wen, Hsu, Wen-Bin, Tang, Chieh-Ju C, Lin, Yi-Nan, Chou, En-Ju, Wu, Chien-Ting, Tang, Tang K
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630357/
https://ncbi.nlm.nih.gov/pubmed/23511974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.56
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