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A specific and covalent JNK-1 ligand selected from an encoded self-assembling chemical library
We describe the construction of a DNA-encoded chemical library comprising 148’135 members, generated through the self-assembly of two sub-libraries, containing 265 and 559 members, respectively. The library was designed to contain building blocks potentially capable of forming covalent interactions...
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| Veröffentlicht in: | Chemistry |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5557334/ https://ncbi.nlm.nih.gov/pubmed/28485044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201701644 |
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