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A specific and covalent JNK-1 ligand selected from an encoded self-assembling chemical library

We describe the construction of a DNA-encoded chemical library comprising 148’135 members, generated through the self-assembly of two sub-libraries, containing 265 and 559 members, respectively. The library was designed to contain building blocks potentially capable of forming covalent interactions...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Zimmermann, Gunther, Rieder, Ulrike, Bajic, Davor, Vanetti, Sara, Chaikuad, Apirat, Knapp, Stefan, Scheuermann, Jörg, Mattarella, Martin, Neri, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557334/
https://ncbi.nlm.nih.gov/pubmed/28485044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201701644
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