CD4(+) T cells mediate antibody-independent acquired immunity to pneumococcal colonization

Acquired immunity to Streptococcus pneumoniae (pneumococcus) has long been assumed to depend on the presence of anticapsular antibodies. We found, however, that colonization with live pneumococci of serotypes 6B, 7F, or 14 protected mice against recolonization by any of the serotypes and that protec...

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Hlavní autoři: Malley, Richard, Trzcinski, Krzysztof, Srivastava, Amit, Thompson, Claudette M., Anderson, Porter W., Lipsitch, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC555733/
https://ncbi.nlm.nih.gov/pubmed/15781870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501254102
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