Antibodies to Conserved Pneumococcal Antigens Correlate with, but Are Not Required for, Protection against Pneumococcal Colonization Induced by Prior Exposure in a Mouse Model

In mice following intranasal exposure to Streptococcus pneumoniae, protection against pneumococcal colonization was independent of antibody but dependent on CD4(+) T cells. Nonetheless, concentrations of antibodies to three conserved pneumococcal antigens correlated with protection against colonizat...

Full description

Saved in:
Bibliographic Details
Main Authors: Trzciński, Krzysztof, Thompson, Claudette, Malley, Richard, Lipsitch, Marc
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230924/
https://ncbi.nlm.nih.gov/pubmed/16177389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.7043-7046.2005
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items