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Protection against Nasopharyngeal Colonization by Streptococcus pneumoniae Is Mediated by Antigen-Specific CD4(+) T Cells

CD4(+) T-cell-dependent acquired immunity confers antibody-independent protection against pneumococcal colonization. Since this mechanism is poorly understood for extracellular bacteria, we assessed the antigen specificity of the induction and recall of this immune response by using BALB/c DO11.10Ra...

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Detalhes bibliográficos
Main Authors: Trzciński, Krzysztof, Thompson, Claudette M., Srivastava, Amit, Basset, Alan, Malley, Richard, Lipsitch, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423086/
https://ncbi.nlm.nih.gov/pubmed/18391006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00141-08
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