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Protection against Nasopharyngeal Colonization by Streptococcus pneumoniae Is Mediated by Antigen-Specific CD4(+) T Cells

CD4(+) T-cell-dependent acquired immunity confers antibody-independent protection against pneumococcal colonization. Since this mechanism is poorly understood for extracellular bacteria, we assessed the antigen specificity of the induction and recall of this immune response by using BALB/c DO11.10Ra...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Trzciński, Krzysztof, Thompson, Claudette M., Srivastava, Amit, Basset, Alan, Malley, Richard, Lipsitch, Marc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423086/
https://ncbi.nlm.nih.gov/pubmed/18391006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00141-08
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