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SpxB Is a Suicide Gene of Streptococcus pneumoniae and Confers a Selective Advantage in an In Vivo Competitive Colonization Model

The human bacterial pathogen Streptococcus pneumoniae dies spontaneously upon reaching stationary phase. The extent of S. pneumoniae death at stationary phase is unusual in bacteria and has been conventionally attributed to autolysis by the LytA amidase. In this study, we show that spontaneous pneum...

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Detalhes bibliográficos
Main Authors: Regev-Yochay, Gili, Trzcinski, Krzysztof, Thompson, Claudette M., Lipsitch, Marc, Malley, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045178/
https://ncbi.nlm.nih.gov/pubmed/17631628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00813-07
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