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SpxB Is a Suicide Gene of Streptococcus pneumoniae and Confers a Selective Advantage in an In Vivo Competitive Colonization Model

The human bacterial pathogen Streptococcus pneumoniae dies spontaneously upon reaching stationary phase. The extent of S. pneumoniae death at stationary phase is unusual in bacteria and has been conventionally attributed to autolysis by the LytA amidase. In this study, we show that spontaneous pneum...

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Autores principales: Regev-Yochay, Gili, Trzcinski, Krzysztof, Thompson, Claudette M., Lipsitch, Marc, Malley, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045178/
https://ncbi.nlm.nih.gov/pubmed/17631628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00813-07
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