Adoptive transfer of phosphoantigen-specific γδ T-cell subset attenuates M. tuberculosis infection in nonhuman primates

Dominant Vγ2Vδ2 T-cell subset recognizes phosphoantigen, and exist only in humans and nonhuman primates. Despite the discovery of γδ T cells for >30 years, a proof-of-concept (POC) study has not been done to prove the principle that Vγ2Vδ2 T-cell subset is protective against M. tuberculosis (Mtb)...

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Udgivet i:J Immunol
Main Authors: Qaqish, Arwa, Huang, Dan, Chen, Crystal Y., Zhang, Zhuoran, Wang, Richard, Li, Shengpu, Yang, Enzhuoa, Yang, Lu, Larsen, Michelle H., Jacobs, William R., Qian, Lixia, Frencher, James, Shen, Ling, Chen, Zheng W.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557270/
https://ncbi.nlm.nih.gov/pubmed/28526681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1602019
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