Immunization of Vγ2Vδ2 T cells programs sustained effector memory responses that control tuberculosis in nonhuman primates

Tuberculosis (TB) remains a leading killer among infectious diseases, and a better TB vaccine is urgently needed. The critical components and mechanisms of vaccine-induced protection against Mycobacterium tuberculosis (Mtb) remain incompletely defined. Our previous studies demonstrate that Vγ2Vδ2 T...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shen, Ling, Frencher, James, Huang, Dan, Wang, Wandang, Yang, Enzhuo, Chen, Crystal Y., Zhang, Zhuoran, Wang, Richard, Qaqish, Arwa, Larsen, Michelle H., Shen, Hongbo, Porcelli, Steven A., Jacobs, William R., Chen, Zheng W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442559/
https://ncbi.nlm.nih.gov/pubmed/30850538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811380116
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