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Secretory phospholipase A(2) modified HDL rapidly and potently suppresses platelet activation

Levels of secretory phospholipases A(2) (sPLA(2)) highly increase under acute and chronic inflammatory conditions. sPLA(2) is mainly associated with high-density lipoproteins (HDL) and generates bioactive lysophospholipids implicated in acute and chronic inflammatory processes. Unexpectedly, pharmac...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Curcic, Sanja, Holzer, Michael, Pasterk, Lisa, Knuplez, Eva, Eichmann, Thomas O., Frank, Saša, Zimmermann, Robert, Schicho, Rudolf, Heinemann, Akos, Marsche, Gunther
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556053/
https://ncbi.nlm.nih.gov/pubmed/28808297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08136-1
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