Secretory phospholipase A(2) modified HDL rapidly and potently suppresses platelet activation

Levels of secretory phospholipases A(2) (sPLA(2)) highly increase under acute and chronic inflammatory conditions. sPLA(2) is mainly associated with high-density lipoproteins (HDL) and generates bioactive lysophospholipids implicated in acute and chronic inflammatory processes. Unexpectedly, pharmac...

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Pubblicato in:Sci Rep
Autori principali: Curcic, Sanja, Holzer, Michael, Pasterk, Lisa, Knuplez, Eva, Eichmann, Thomas O., Frank, Saša, Zimmermann, Robert, Schicho, Rudolf, Heinemann, Akos, Marsche, Gunther
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556053/
https://ncbi.nlm.nih.gov/pubmed/28808297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08136-1
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