Secretory phospholipase A(2) modified HDL rapidly and potently suppresses platelet activation

Levels of secretory phospholipases A(2) (sPLA(2)) highly increase under acute and chronic inflammatory conditions. sPLA(2) is mainly associated with high-density lipoproteins (HDL) and generates bioactive lysophospholipids implicated in acute and chronic inflammatory processes. Unexpectedly, pharmac...

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Publicat a:Sci Rep
Autors principals: Curcic, Sanja, Holzer, Michael, Pasterk, Lisa, Knuplez, Eva, Eichmann, Thomas O., Frank, Saša, Zimmermann, Robert, Schicho, Rudolf, Heinemann, Akos, Marsche, Gunther
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556053/
https://ncbi.nlm.nih.gov/pubmed/28808297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08136-1
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